Manchester United warmed up for the second leg of their Carling Cup semi-final with Manchester City by going top of the Premier League, with a 4-0 win over Hull City.
Wayne Rooney scored all four goals as United leapfrogged Arsenal and Chelsea to reach the summit with 50 points.
Manchester City also go into the game on the back of a win after beating Scunthorpe United 4-2 at Glanford Park, in the FA Cup on Sunday.
City head to Old Trafford with a one goal advantage, following Carlos Tevez's double at Eastlands last week. The Argentinian took great delight in scoring against former employers, as City came from a goal down to win the tie 2-1.
United arrived at the semi-final stage after beating Wolverhampton Wanderers, Barnsley and Tottenham Hotspur in a repeat of last year's final. Darron Gibson scored twice in the first half to wrap up the victory and set up the derby clash.
City on the other hand overcame Crystal Palace, Fulham, Scunthorpe United and Arsenal, when goals from Carlos Tevez, Shaun Wright-Phillips and Vladimir Weiss secured a 3-0 win.
Manchester City could be boosted by the return of striker Emmanuel Adebayor, who has been on compassionate leave, since the attack on the Togo team bus before the start of the African Nations Cup.
"It is important that he is well and that he is concentrating on the game tomorrow," Roberto Mancini told www.mcfc.co.uk.
" There is a chance he will be on the bench, he will only have trained twice with the squad since coming back, but having seen him I think he will be ready to play some part.
"He trained with us on Monday for the first time and came through OK. I have spoken with him about what happened when he was away, he's very quiet but he is focussed on the game with United. There is no problem with him for tomorrow."
HEAD TO HEAD
This will be the 154th meeting between the two sides in all competitions, the first of which came way back in 1894, when United beat City 5-2 at Hyde Road. The red half of Manchester was celebrating again later in the season when they won the reverse fixture 4-1 at Bank Street.
United lead the head to head charts with 62 wins compared to City's 42 while 49 matches have ended all square.
Manchester United will be at full strength for the visit of city, one man who won't be available though is Danny Welbeck, who played in the first three matches in the competition, after he joined Preston North End on loan until the end of the season.
"There are no new injuries," the boss told www.manutd.com.
"Everyone came through from Saturday. I have a big, strong squad. It's going to be a fantastic game, I know that. Maybe even better than last week's. We're ready for it and we hope that our experience helps."
As we have previously mentioned Emmanuel Adebayor could be set to make his return for Manchester City, after returning from compassionate leave.
Kolo Toure could also return after the Ivory Coast were knocked out of the African Cup of Nations by Algeria but Patrick Viera will have to wait to make his debut as he is still suffering with a calf problem.