Wolves manager Dean Saunders bemoaned his side's bad luck after substitute Jonathan Obika hit a late winner for in a 2-1 victory for Charlton.
Wanderers dropped back into the npower Championship relegation places after the 90th-minute strike earned Charlton a home victory
Kevin Doyle had headed in an equaliser after Dorian Dervite had opened the scoring for the Addicks but Wolves failed to hang on for a draw.
"Football is cruel isn't it?" Saunders said. "Both their goals are scrambled. It was not our day.
"Karl Henry hits a 35-yarder, which hits the underside of the bar and comes out. If it is your day that goes in.
"The first goal is a mis-kicked corner, which he scuffs along the floor. Kevin Doyle has tried to clear it but it is like a low ball in crickets and he miss hits it.
"The second goal is even more unlucky in the 90th minute when it hits Jack Robinson in the face and squirts out to their player when it could have gone anywhere."
It was Obika's second late winner in as many home games after he scored against Leeds at the Valley, with this victory taking Charlton's unbeaten run to six matches.
Addicks boss Chris Powell said: "Obika shows the value of having a squad. He has been top class since he came into the dressing room.
"He is good finisher, when he doesn't start he wants to be involved, he always gets chances, which is a good trait for a striker. On top of that Jonathan is a good character and deserves hero status for the day."