Barnsley v Watford
Barnsley remain with just one win so far in the Sky Bet Championship and they welcome promotion hopefuls Watford.
The Tykes' only three-pointer to date came against Huddersfield Town but they have lost their two games since, taking their defeat tally to five.
Watford lie sixth having won three and drawn three, and lost once, in their opening seven games. They beat Doncaster Rovers last time out and have been defeated by Barnsley only once in six meetings.
Birmingham City v Sheffield Wednesday
Birmingham City and Sheffield Wednesday sit side-by-side on four points towards the bottom of the Sky Bet Championship table and clash at St Andrews.
The Blues are the lower of the two but they have tabled a win, against Yeovil Town, whereas Wednesday remain without a victory but have played a game less.
Dave Jones' side's four points have come from four successive draws, picked up in their most recent four outings.
Blackburn Rovers v Huddersfield Town
It's Lancashire against Yorkshire at Ewood Park on Saturday as Blackburn Rovers entertain Huddersfield Town.
Both teams have enjoyed reasonable form of late with 11th-placed Huddersfield losing once in six, registering three victories, and Blackburn winning two of their last four after a winless three-game start to the season.
If the Terriers do chalk up an away victory, it will be the first time since 1999 that they have come out on top against Rovers.
Blackpool v Leicester City
It's second against third at Bloomfield Road with Blackpool hosting Leicester City.
The Tangerines were knocked off top spot in midweek as they suffered their first defeat of the season, against Millwall, and they now lie behind the second-placed Foxes.
Nigel Pearson's men have the same overall record as Blackpool but have scored one more goal. They haven't lost to the Seasiders since 2008, six meetings ago.
David Nugent scored Leicester City's second goal in their 2-1 midweek win over Blackburn Rovers
Brighton and Hove Albion v Bolton Wanderers
Bolton are now the team propping up the rest in the Sky Bet Championship and they are on the road to the South Coast to face Brighton and Hove Albion.
The Trotters have failed to carry on their impressive form from the back end of last season when they narrowly missed out on the Play-Offs, having begun this term with three draws and four defeats.
Brighton got off to a stuttering start, losing their opening two, but they are now unbeaten in five, although their most recent three games have all ended level.
Charlton v Millwall
There's a televised South London derby at The Valley where Charlton Athletic take on Millwall at 12:15pm.
The travelling Lions pulled off an unlikely win against Blackpool on Tuesday and that was enough for them to climb off the bottom and move up to 19th. Charlton are two places further ahead with the same points total, but they've played a game less.
Millwall have the upper hand in recent games between the two clubs, triumphing in two of the last four, with the other two clashes ended level. The Addicks haven't managed to score against the Lions in three meetings.
Derby County v Reading
After a dramatic midweek triumph against Leeds United, Reading make the trip to Pride Park where they meet Derby County.
Adam Le Fondre scored the winner for the Royals on Wednesday six minutes into injury time and that victory lifted them up to seventh, while Johnny Russell scored a brace for Derby in their 2-2 draw with Bolton Wanderers a night previous.
The Rams have won just one encounter against Reading since 2005, 13 games ago.
Doncaster Rovers v Nottingham Forest
Nottingham Forest head to South Yorkshire to play Doncaster Rovers.
Billy Davies' fifth-placed side fought back from a 2-0 deficit against Middlesbrough on Tuesday night to grab a share of the spoils.
Rovers lost 2-1 at Watford to leave them 18th in the table with five points.
Darius Henderson completed Nottingham Forest's fight back in their 2-2 draw against Middlesbrough on Tuesday
Leeds United v Burnley
Burnley make the journey to Elland Road on Saturday to lock horns with Leeds United.
After avoiding defeat in their opening four league games, Leeds have lost two of their last three outings, including Wednesday's 1-0 reverse at Reading. Fourth-placed Burnley have lost just once this term and beat Birmingham City 3-0 in their most recent game.
Only one of the last seven meetings between the sides has ended in Burnley's favour - the Clarets registered a 1-0 victory against Leeds at Turf Moor last season with a Charlie Austin strike.
Middlesbrough v Bournemouth
Middlesbrough and Bournemouth will meet for the first time in over 20 years this weekend.
The last time the two clubs clashed was in the League Cup back in 1991 and on that occasion Boro went through 2-1 in a replay, but it is Bournemouth who head into the fixture with better form.
The Cherries have four wins and three losses from their opening seven games, while Tony Mowbray's men have just one victory to their name and they are amidst a five-game winless run.
Wigan Athletic v Ipswich Town
On Sunday, Wigan Athletic entertain Ipswich Town at the DW Stadium.
Mick McCarthy's men have taken seven points from their last three games with a draw against Birmingham City coming before victories over Middlesbrough and, most recently, Yeovil Town.
The Latics are down in 15th and weren't in midweek league action as they played their first ever European tie, drawing 0-0 with Belgium's Zulte-Waregem.
Yeovil Town v Queens Park Rangers
Top of the table Queens Park Rangers are on their travels this weekend as they are welcomed by Yeovil Town.
QPR moved to the Sky Bet Championship's summit on Wednesday night after a goalless draw against Brighton, while Yeovil have struggled since winning on the opening day of the campaign - they have picked up one point from their last six games.
The clubs have met just twice; Rangers ran out 3-0 winners in the FA Cup in 1988 but Yeovil were the victors in the most recent encounter - 3-0 in the 2001/02 Football League Trophy.
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