Reading are waiting to find out the extent of Jordan Obita's calf injury.
The winger limped off during Monday night's 1-1 draw with Leicester to join a growing casualty list.
Boss Nigel Adkins was already without Hope Akpan, Danny Guthrie and Jem Karacan and had to patch up the likes of Danny Williams, Garath McCleary, Wayne Bridge and Mikele Leigertwood to play.
Midfielder Leigertwood showed his rustiness after a year on the sidelines when he was sent off for two clumsy challenges.
Adkins said: " We went into the game playing chess, knowing we'll get an hour out of this person or half an hour out of some.
"Will Jordan be okay for the other games? We'll have to wait and see.
"With Garath, we're playing him and not playing him, then he's training and not training. With Danny Williams, b y the time he got to 60 minutes he'd blown up, and I don't know how his knee will react now.
"That's the problem with Bridgey too, several players. It's a case of seeing how much we can get from them, knowing there's a risk they can break down.
"Leigertwood has been rushed back, he's been out a year, and to ask him to be a monumental player is a big ask. It's a shame he's out of the next game.
"Hope did a bit of training after the game, we'll see if we can get him somewhere near for Friday."