Leicester City are already through to the third round of the Johnstone's Paint Trophy following their penalty shootout win over Lincoln City and 30 other teams will be bidding to join them this week.
The Foxes switched their clash due to international call-ups, which is also the reason for Tranmere Rovers taking on Crewe Alexandra tonight.
With clubs invoking a 5-day rule ahead of the weekend's full international programme Rovers will have both Ian Goodison (Jamaica) and Edrisso Sonko (Gambia) available to play.
Bury and Stockport County go head to head in one of the picks of the Northern section, with top of League 2 playing League 1 new boys. Bury received a bye for the first round so this is their first appearance in the competition this season.
Alan Knill picked up the Manager of the Month award for September after his side remained unbeaten so far this season and he will be relishing the chance for his side to pit their wits against County.
Jim Gannon's have adapted well to Coca-Cola League 1 after winning promotion via the Play-Offs in May and will be looking to build on their impressive 3-1 victory over Oldham Athletic on Friday night.
Chester City are another team who received a bye in the last round and they face a tricky home tie against Morecambe. Simon Davies had a horrendous start to the campaign, losing the opening four games in all competitions, conceding 16 goals along the way. But since their 5-1 home win over Barnet on August 30th City haven't looked back with only one defeat in their last six matches.
In the southern section, the tie of the round has to be Brighton & Hove Albion against Leyton Orient, with Micky Adams' side already proving to be a quality cup side. The Seagulls are through to Round 4 of the Carling Cup after knocking out Manchester City but Orient will provide very different opposition.
You can see a full list of tonight's fixtures and offers on admission prices by visiting our dedicated Johnstone's Paint Trophy section.