THE BIG MATCH
The eye catching fixture in Coca-Cola League 1 sees two of the division's new boys go head to head. One will be hoping they can continue where they left off, while the others will be hoping for a dramatic change of fortune as Charlton Athletic host Wycombe Wanderers.
11 players have left the Valley including big names Matt Holland, Nicky Weaver and Darren Ambrose, while Phil Parkinson has bought in just three players so far- Miguel Llera (MK Dons), Frazer Richardson (Leeds United) and Christian Dailly - as he looks to take his side back up at the first attempt.
For Wycombe they will hope their momentum can see them follow in the footsteps of Peterborough United who made it successive promotions when they went up to the Coca-Cola Championship in May and the players admit it will be a far cry from some of their fixtures last season:
Brett Pittman told www.wwfc.com: "I was buzzing when I saw the fixtures. The first game away at Charlton is a good one to start with and it'll be a massive game.
"The pressure will be on Charlton to perform, but we will put pressure on ourselves to perform.
"Everyone is really excited about getting started, as we don't get to play in big stadiums like we will next season very often."
DAVID VERSUS GOLIATH
Exeter City will have a baptism of fire when they travel to Elland Road to face Leeds United.
The Grecians have also managed back to back promotions going from the Conference to where they are today in just two seasons but despite that midfielder and former Leeds trainee Barry Corr believes they can cause an upset on Saturday.
"They aren't the Leeds of old, we can go there and win the game," Corr told Exeter's official website www.exeterfc.co.uk
"They play infront of a big crowd and they are obviously a very good side but there is no reason why we can't go there and win.
"Following promotion to be straight into playing Leeds then a big cup game against QPR and then Norwich is fantastic."
Leeds on the other hand know that the pressure will be back on them this season to get back to the Coca--Cola Championship, after missing out on last season's Play-Offs. They will have to do it without Fabian Delph, who has joined Aston Villa, but Simon Grayson is confident he still has the players to succeed.
Speaking to www.leedsunited.com he said: "I genuinely feel I have a squad capable of doing it without any major strengthening.
"I have one or two targets lined up and we'll see where we go with them, but any money we spend will be spent wisely. I'm not going to spend any money just for the sake of it.
"When you look at Fab's position, we have players who are capable of playing there. Prutts did well there last Saturday, there's Neil Kilkenny, Bradley Johnson, and we have players who fit the bill who are already here."
THE NEW BOYS
Southampton face Millwall in their first game in League1 and all the action will be live on Sky Sports. The Saints start the campaign on minus 10 points but with a new Chairman and new Manager in Alan Pardew they will be looking to close down that deficit as soon as possible.
Milwall on the other hand will be looking to go one better than last season, when they lost out to Scunthorpe in the Coca-Cola League 1 Play-Off Final.
Brentford face the tricky trip to Carlisle , while Gillingham host Swindon Town and Norwich City take on Colchester at Carrow Road.
ON THE BOX
It's 74 days since the last televised game in the Football League but you can certainly make up for it over the next few days with no less than six games in the next five days! You can read our full in depth look at the televised games by clicking here
Kicking off tonight it's the match from the Riverside where Middlesbrough take on Sheffield United in the season opener before Southampton's clash with Millwall gets underway at lunchtime on Saturday. West Brom's home tie with Newcastle signals the return of the Football League to the BBC at 5.30pm on Saturday. Ipswich Town's trip to Coventry City's is Sunday's offering before the Carling Cup first round matches between Darlington and Leeds on Monday and Bury and West Brom on Tuesday - Please click here for the full list of televised games.
For all this weekend's Football League fixtures click here