Wycombe manager Gareth Ainsworth admitted his side had survived an "onslaught" after Wanderers stole away from Home Park with a 1-0 victory.
The Chairboys scored early on through Matt McClure in their only meaningful attack of the game to steal the points in a real Devon smash and grab raid. McClure - back after a Boxing Day ban - won the game in the 11th minute just seconds after Argyle striker Nick Chadwick had seen his shot on the turn cannon off a post.
They had to withstand concerted Plymouth pressure from beginning to end to claim the three points, leaving player-manager Ainsworth to reflect with pride on their backs-to-the-wall efforts.
"When things are going well and we're attacking well, the game becomes easy," he said. "But, with the onslaught we had to stand up to - in the second half especially - I thought the lads were absolutely outstanding. In its own way, it's probably one of the best performances under me so far.
"We didn't attack as well as we can. It was a real team effort, a real Wycombe performance. The lads were superb. It's a tough place to come and win. I've not won many times in my career here. It's a really good scalp."
Argyle made all the running, with Nick Chadwick, Robbie Williams, Paris Cowan-Hall and Conor Hourihane all coming close to making a first-half breakthrough. It was much more of the same after the interval, with Cowan-Hall hitting the bar and both Chadwick and Darren Purse heading narrowly wide.
And Plymouth boss Carl Fletcher bemoaned his players' inability to turn their pressure into goals in a defeat which leaves Plymouth looking over their shoulders at the wrong end of npower League Two.
"We dominated about 90% of the game," he said. "Wycombe had one chance and scored, and we didn't score. That was about it. In everything apart from the final third, we were really good - the lads' effort and work-rate was great - but we didn't put the ball in the back of the net.
"That was the difference in the whole game. We dominated from start to finish but couldn't get that goal. We lacked a bit of quality in the final third, the make-or-break area. It's disappointing not to get a goal from our dominance.
"On performances, we shouldn't be anywhere near where we are but you deal with the situation that's thrown at you. It's obviously disappointing not to get a result because we've been on a good run and should have got a lot more."