Brentford chairman Greg Dyke will leave Griffin Park in the summer to become the new chairman of the Football Association.
The FA board has unanimously approved the nomination of Dyke, 65, to succeed David Bernstein when he leaves the post in July.
The appointment is subject to the approval of the FA council.
Dyke said: "Obviously as chairman of the FA it is imperative that I am neutral so that means giving up my current role as chairman of Brentford, which I will miss.
"However, I shall be staying on until the end of the season.
"As I leave I would like to pay tribute to everyone at Brentford, the staff, the players and manager and particularly the fans. I hope their loyalty is rewarded with promotion, it deserves to be.
"I am very excited to take on this role with the FA."