Bristol City v Brentford
Bristol City's search for a first victory will continue on Tuesday night when they host Brentford.
The Robins lost late on at Crewe Alexandra on Saturday and, following that result - their 11th winless game - they slumped to the bottom of the Sky Bet League 1 table.
Brentford were 3-1 winners at home to Colchester United and that victory ended their run of successive defeats.
Coventry City v Leyton Orient
League 1 leaders Leyton Orient remain unbeaten and visit Coventry City.
The O's overcame Tranmere Rovers 4-0 on Saturday, leaving them sitting pretty at the top on 32 points, while their opponents Coventry picked up a valuable point away at third-placed Wolverhampton Wanderers.
Goals are guaranteed in this fixture with the Sky Blues scoring 16 and conceding 13 in the six games they have played at Sixfields this term. Orient have netted 15 away goals - the second best return in the league.
Kevin Lisbie scored two of Leyton Orient's four goals at Tranmere on Saturday
Crawley Town v Port Vale
Crawley Town welcome Port Vale to West Sussex.
The Red Devils have impressed at home this term with four victories, one draw and just one defeat to date, and they are currently on a seven-match unbeaten streak.
Port Vale have never tasted success against Crawley and come into the match after a 2-1 loss to Sheffield United.
Crewe Alexandra v Stevenage
Crewe Alexandra have notched back-to-back wins for the first time this term and now host Stevenage.
The Alex only had one victory prior to the two three-pointers they recorded against Preston and, most recently, Bristol City, and their upturn in form has lifted them to 16th although they are yet to get the better of Stevenage, drawing two and losing two of the four matches played.
Graham Westley's team are down in 21st and have lost five of their last six, including Saturday's outing at Walsall.
Gillingham v Notts County
Gillingham and Notts County both languish towards the bottom of the Sky Bet League 1 table and they clash in Kent.
The Gills are the higher of the two in 19th but suffered their second consecutive loss on Saturday, against Preston, while the 23rd-placed Magpies were defeated 2-0 by Swindon Town last Friday.
The two clubs haven't met since the 2008/09 League 2 season and, during that campaign, Gillingham notched four points over the two matches on their way to promotion.
Milton Keynes Dons v Carlisle United
Milton Keynes Dons got back to winning ways on Saturday and now entertain Graham Kavanagh's Carlisle United.
Karl Robinson's men had lost two games on the spin but secured three points with an entertaining 3-2 triumph at home to Rotherham United.
The Cumbrians come into the midweek encounter having lost 1-0 at Oldham Athletic, and that defeat brought to an end their four-match unbeaten run.
Peterborough United v Sheffield United
Peterborough United and Sheffield United have endured contrasting starts to the League 1 season and meet at London Road.
While Posh are flying high in second, just a point adrift of leaders Leyton Orient, Sheffield United are 20th after securing just their second win of the season last time out, against Port Vale.
The Blades are yet to pick up any points on the road and will be up against it when they face Peterborough, who have won five of their first six home matches.
Preston North End v Bradford City
Lancashire meets Yorkshire at Deepdale, where Preston North End and Bradford City go head-to-head.
The two sides have enjoyed fine starts to this season and sit side-by-side in the Play-Offs after 12 matches.
Both have six victories but Preston - 2-1 winners at Gillingham on Saturday - sit the higher, in fourth, having accrued one more point than the Bantams, who have lost their last two, against Tranmere Rovers and Crawley, without scoring.
Rotherham United v Tranmere Rovers
Rotherham United have lost three of their last four and take on lowly Tranmere Rovers.
The Millers have been defeated by Peterborough, Swindon and MK Dons in recent weeks, with a 1-0 success against Brentford, two games ago, the only positive.
Ronnie Moore, who has managed Rotherham on two separate occasions, has seen his Tranmere side lose five of their last six, but their only two triumphs to date have both come on the road.
Shrewsbury Town v Colchester United
Two mid-table sides, Shrewsbury Town and Colchester United, come together in Shropshire.
The pair are tied on 12 points in the table with an identical record but the Shrews sit one place higher in 13th by virtue of a better goal difference.
Both were defeated last time out and Colchester's loss means they haven't won since the second week of the season. They are also winless against Shrewsbury since a 2005 FA Cup success.
Swindon Town v Walsall
Swindon have the joint-best home record in the division and host Walsall on Tuesday.
The Robins have won five of their six games at the County Ground and collected a valuable three points at home to Notts County last Friday - their third win on the bounce - which lifted them into the Play-Offs.
Walsall are ninth and, along with four other teams, are just a point adrift of Swindon. They ended a four-game wait for a victory by beating Stevenage 2-1 on Saturday.
Nile Ranger celebrates after scoring the opening goal in Swindon's 2-0 win against Notts County last Friday
Wolverhampton Wanderers v Oldham Athletic
Third-placed Wolverhampton Wanderers welcome Oldham Athletic to Molineux.
Kenny Jackett's men were denied all three points by a late Coventry City equaliser at the weekend, which saw them slip five points behind second-placed Peterborough, although they've played a game less.
The Latics sit 18th and have lost just once in four. They were 1-0 winners against Carlisle on Saturday, which was their third success of the campaign.
Click here for all of the midweek action