Exeter manager Paul Tisdale could not hide his frustration after watching his side go down to their sixth home npower League Two defeat in 12 games to Oxford.
The U's stormed into a three goal lead with James Constable scoring twice and Peter Leven also netting before Jamie Cureton scored a consolation penalty for the Grecians, his 16th of the campaign.
"It's frustrating for me, the fans and the players as well," Tisdale said. "We have to look at every situation objectively and it is my job to try and alter this trend we have of poor results at home."
He added: "Sometimes, when things are disjointed as they were for large parts of today's game, it gives you a simple path ahead. You do have to make some strong changes in your mind and the way you set your team up. It was very frustrating today.
"I am not going to make a thing of it. I am certainly very happy with our away form and I don't want to meddle with that. I am trying to put out the same players to be good away and be good at home, but trying to find a solution for those same 11, 12 players that play virtually every week is hard."
Oxford boss Chris Wilder praised his side for what he felt was a professional job. The U's were good value for their win and could have won by a bigger scoreline.
"It was always going to be a tough game for us but we weathered the early storm which we knew would come," he said.
"We stuck in there and gradually got on top. They had three men in the middle of the park, so it was on for us to get it wide and that drove them back.
"I was maybe a touch disappointed at half-time that we have not increased our lead. But we scored two terrific goals after the break and I am delighted that we took all the points. The way we have gone about our performance has rewarded the players and the supporters.
"I looked at the fixture list today and the maximum any away team has had to travel is 90 minutes and we have to go three and a half hours. No away team has had to travel overnight apart for us, so maybe next year the club might get a Boxing Day home fixture. I am slightly annoyed why the fixture came out this way, but we prepared properly and we have been rewarded."