Burton Albion v Oxford United
Burton Albion and Oxford United are both unbeaten on 11 points after five matches and they come together at the Pirelli Stadium on Saturday.
The U's sit one place above the Brewers, in second, having scored three more goals. They won their opening three matches but have been held to draws in their last two.
Burton have also drawn two and won three. They ran out 1-0 victors in their most recent fixture, against Accrington Stanley, with Adam Reed scoring a last-gasp winner.
Cheltenham Town v Portsmouth
Cheltenham Town and Portsmouth remain in the bottom half with just one win each and they go head-to-head at Whaddon Road in their first competitive meeting.
The Robins' only win so far this season came against Accrington Stanley, while Pompey's was against Morecambe.
Both teams come into the fixture having lost last time out - Cheltenham went down 4-1 to Bury and Portsmouth were defeated 2-0 by Chesterfield.
Chesterfield v Accrington Stanley
That 2-0 win for Chesterfield against Portsmouth lifted the Spireites to the summit of the division and they take on bottom club Accrington Stanley on Saturday.
The table-toppers remain unbeaten and have dropped points on just one occasion so far, taking 13 from their opening five matches.
Accrington have only managed to chalk up a single point over that period and have lost their last three on the spin.
Dagenham and Redbridge v Exeter City
Dagenham and Redbridge have collected four of their five points on home soil and they entertain Exeter City.
The Daggers have overcome York City and drawn with Newport County at the London Borough of Barking and Dagenham Stadium, and also beat League 1 Colchester United 4-1 in front of their home fans in the Johnstone's Paint Trophy in midweek.
Exeter have begun well and sit fifth on 10 points. They were victorious at home to York last weekend.
Fleetwood Town v Torquay United
In Lancashire, Graham Alexander's Fleetwood Town host Alan Knill's Torquay United.
Fleetwood have two losses, to Torquay's one, but it's the Cod Army who sit higher as they have chalked up three wins compared to the Gulls' solitary success, against Northampton Town in their last away trip.
The Cod Army are yet to taste defeat against Torquay with the first ever meeting between the two teams last season ending goalless, and the second finishing in their favour.
Fleetwood Town were in midweek Johnstone's Paint Trophy
action against Tranmere Rovers and ran out 2-1 winners courtesy of a Jamille Matt brace
Hartlepool United v Wycombe Wanderers
Hartlepool United will continue their search for a first League 2 win, and their first league goal, when they welcome Wycombe Wanderers.
Pools are down at the foot of the division on two points and are the only Football League side yet to hit the back of the net. They did smash five past Bradford City without reply in the Johnstone's Paint Trophy in midweek, though.
Wycombe's form has been somewhat indifferent with two wins, two defeats and a draw. The Chairboys recorded an impressive 2-1 success against Southend United in their last league outing.
Newport County v Mansfield Town
Newport County and Mansfield Town have both begun well after winning promotion to The Football League last term and they meet in Wales.
The pair have collected eight points each from the first five matches with the same run of form.
The Exiles are unbeaten in three, collecting a win and two draws, while the Stags haven't lost since an opening day defeat against Scunthorpe United.
Northampton Town v Scunthorpe United
Brian Laws' Scunthorpe visit under-performing Northampton Town this weekend.
Aidy Boothroyd's Cobblers, who were defeated in last season's League 2 Play-Off Final, have lost all but one of their opening five games and sit 22nd on three points.
Scunthorpe have also registered just one win but they have lost only once, drawing the other three, most recently against Newport.
Gary Deegan celebrates against Newport County in Northampton Town's only win of the campaign.
Plymouth Argyle v Bristol Rovers
Plymouth Argyle and Bristol Rovers have both notched two victories and come together at Home Park.
Rovers' two wins have come in their most recent two outings as they beat York City 3-2 before seeing off Northampton 1-0. They come into the game after a defeat having lost 2-1 to rivals Bristol City in the Johnstone's Paint Trophy on Wednesday.
Plymouth were also defeated in their last match, against Morecambe, but won their two games prior to that - 3-1 at Cheltenham Town and 1-0 against Rochdale.
Rochdale v Bury
The stand-out fixture in Sky Bet League 2 this weekend sees Rochdale and fierce rivals Bury lock horns at Spotland.
Keith Hill's Dale haven't won since the first day of the season, while the Shakers are unbeaten in three with two wins and a draw following two losses in their opening two games.
The rivals haven't met in a league fixture since the 2011/12 League 1 season and, during that campaign, Rochdale won both encounters.
Southend United v Morecambe
Morecambe make the journey to Roots Hall on Saturday to play Southend United.
The Shrimps have experienced an upturn in fortunes in the last two matches, collecting wins against both Exeter City and Plymouth Argyle.
On the flip side, Southend have lost their most recent two, following three victories in their first three outings.
York City v AFC Wimbledon
York City and AFC Wimbledon both struggled against relegation last term but have had contrasting starts this time around - they meet at Bootham Crescent on Saturday.
The Minstermen finished four points above the drop zone last season and have only collected four points from the first five games, with their only win coming against Northampton on the first day.
Neal Ardley's Wombles, who ended last term just two points above danger, have fared much better than York and sit fourth on 10 points. They've picked up three victories, including two in their last two matches.
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