Accrington Stanley v Exeter City
Exeter City travel to Accrington Stanley looking for their third successive victory against the Lancashire outfit.
The 11th-placed Grecians completed the double over Stanley last term, winning 2-0 at home and 3-0 away, but come into this weekend's meeting without a victory since mid-October, seven matches ago.
Accrington lost 1-0 at Northampton in their most recent outing and that ended their eight-game undefeated spell - form that lifted them out of the relegation zone and up to 19th.
AFC Wimbledon v Mansfield Town
Mansfield Town are Sky Bet League 2's out-of-form team and they travel to AFC Wimbledon.
The Stags were third when they last picked up a three-point haul, 10 league games ago, but they've since plummeted to 18th - a mere four points above the bottom two. They recorded a respectable 1-1 draw at League 1 club Oldham Athletic in the FA Cup last Saturday.
Wimbledon are 12th and winless in three, but they've lost just once on home soil this term.
Burton Albion v York City
Burton Albion have three wins on the spin and host York City at the Pirelli Stadium.
The Brewers have overcome Bristol Rovers, Mansfield and Plymouth all by a 1-0 scoreline to register a hat-trick of successive league victories, and that has lifted them to sixth, alongside four other teams within a point of leaders Oxford.
York have failed to triumph in their most recent five, drawing four, and they are just two points above the relegation zone, sitting 21st.
Bury v Northampton Town
It's 20th against 23rd at the JD Stadium with Bury welcoming the visit of Northampton Town.
The game between the two Sky Bet League 2 strugglers will be David Flitcroft's first in charge of Bury after the former midfielder took over on Monday. Prior to his appointment, the Shakers recorded three draws and a solitary win from their most recent four.
Northampton beat Accrington last time out in the league but were defeated 2-0 at non-league Grimsby Town in last weekend's FA Cup second round.
Cheltenham Town v Hartlepool United
Cheltenham Town and Hartlepool United sit side-by-side in the Sky Bet League 2 table and clash on Saturday.
The Robins are the higher of the two, in 13th, after they stretched their unbeaten run to eight matches with victory at Morecambe last Saturday, while Hartlepool drew with Coventry City in the FA Cup.
Cheltenham have lost only once to Hartlepool since 2001 and that was when the pair were last in the same division, during the 2008/09 League 1 campaign.
Chesterfield v Plymouth Argyle
John Sheridan's Plymouth Argyle are on the road this weekend to visit the manager's former club, second-placed Chesterfield.
The Pilgrims lost for the first time in six in their most recent league outing but bounced back to keep their involvement in the FA Cup alive last weekend by seeing off Welling United, 3-1.
Paul Cook's Spireites succumbed to a 3-1 loss at home to Southend to be knocked out of the FA Cup, but have won five of their 10 league games at the Proact Stadium, conceding just seven goals.
This weekend, John Sheridan takes his Plymouth side to his former club Chesterfield, who he led to Johnstone's Paint Trophy
victory in 2012
Morecambe v Bristol Rovers
Bristol Rovers have a chance to improve their torrid away form when they travel to Morecambe at the weekend.
John Ward's men have won only once on their travels so far, at Oxford United in November, with six of their away matches ending in defeat. That has contributed to their poor league position of 22nd.
Morecambe are 10th, three points off the Play-Offs, but are on an inconsistent run with only two wins in nine. They lost 1-0 at home to Cheltenham last weekend.
Oxford United v Dagenham and Redbridge
Sky Bet League 2 leaders Oxford United are at home to Dagenham and Redbridge.
The U's have drawn their most recent two following back-to-back wins. They have a one-point advantage over the five teams below them in the League 2 table, highlighting how tight it is at the top of the division.
The Daggers are ninth but only four points behind their weekend opponents. Six of their eight wins have come at home but Oxford have only notched three victories at the Kassam this term.
Portsmouth v Newport County
Richie Barker takes charge of Portsmouth for the first time with Newport County the visitors.
Barker succeeded Guy Whittingham in the managerial seat at Fratton Park after recently leaving his role at League 1 Crawley. His immediate task will be to arrest Pompey's run of five games without a victory, which has seen them slip to 17th.
Justin Edinburgh's Exiles are eighth but have only won once on their travels. They've already played Portsmouth this term, winning 3-0 in a Johnstone's Paint Trophy tie.
Richie Barker's Portsmouth welcome Newport County to Fratton Park this weekend, for the 38-year-old's first game in charge of the South Coast outfit
Rochdale v Fleetwood Town
Rochdale and Fleetwood Town are both in the mix at the top of the division and come together at Spotland.
Dale are one of the five teams within a point of leaders Oxford but they've failed to win in their last two outings. Fleetwood are also without a victory in two, and trail Rochdale by a single point.
Keith Hill's side have seven wins from their 10 home matches, with 20 goals netted over that period,. The Cod Army have the second best away defensive record, conceding just eight goals in their nine matches on the road.
Torquay United v Southend United
Rock-bottom Torquay have lost three of their last four and face in-form Southend United.
While the Gulls have been defeated by Chesterfield, Accrington and Scunthorpe recently, with a solitary point against Plymouth in between, Southend have registered four victories and a draw to surge up to third.
Phil Brown's side trail leaders Oxford by a point and have the wind in their sails. Torquay possess the division's worst home record with one win in nine at Plainmoor.
Wycombe Wanderers v Scunthorpe United
Gareth Ainsworth's out-of-sorts Wycombe Wanderers are at home this Saturday, against a resurgent Scunthorpe United.
The Chairboys haven't won since 19th October, collecting just three points from a possible 21 in their last seven matches.
Since appointing Russ Wilcox and Tony Daws to the managerial seat, following the dismissal of Brian Laws, the Iron have chalked up three successive wins, and they now find themselves fourth, with momentum.
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